· mRNA is made when the double helix of the DNA unwinds revealing the part that carries the particular instructions for a specific protein.
· one of the DNA strands is used as a template for the synthesis of mRNA. mRNA is a single strand.
mRNA carries instructions it has obtained from the bit of the DNA that unrolled, to the factory to be made up. The factory is called a ribosome.
The factory is still inside the cell where the DNA is. However, the DNA is in the nucleus of the cell and the ribosome is in the outer jelly like cytoplasm
Cells are amazing hives of activity.
· These instructions to make up a protein - like a spike protein or enzyme - may be a) translated immediately into a protein b) stored for later c) degraded immediately
with an mRNA jab there is no template from DNA which would perpetually produce spike protein. It is simply a set of injected instructions which go to the ribosome to be made up into spike protein where it can follow abc as mentioned above.
· mRNA will eventually degrade.
Key words, DNA, mRNA and ribosome
DNA is the master plan
mRNA is the messenger boy taking the master plan instructions to the factory (ribosome)to be made up.
The protein is put on display for the immune system to take a look at.
Most of the time it is happy with protein instructions contained within our own DNA.
However, it is NOT happy with spike protein and mounts defensive actions against the interloper. This is what makes us feel ill. It is not the spike protein that makes us feel ill, it is the immune system's reaction to it.
If the spike protein has been 'sampled' by the immune system then antibodies will have been formed to respond to this foreign body.
Antibodies made against ordinary common cold coronaviruses last a lifetime.